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New Studies Confirm Benefits of CRS-HIPEC

As mesothelioma researchers and physicians continue to work towards improving treatment protocols for malignant peritoneal mesothelioma, information is being released showing various methodologies that are improving outcomes. Three separate international studies have just been published in support of the procedure known as Heated Intraperitoneal Chemotherapy, or HIPEC, in which heated chemotherapy drugs are administered directly into the surgical site following surgery to remove mesothelioma tumors. The drugs are then used as a post-operative rinse in order to remove as many remaining cancer cells as possible in order to stop or delay the return of the tumor.

The HIPEC treatment is relatively new and is not available at all cancer centers, but it is becoming increasingly accepted. The three studies were each aimed at finding ways to improve upon what is already being done.

In Canada, researchers have followed the use of the procedure for eight years, using the chemotherapy drug oxaliplatin. Between 2004 and 2012, the University of Montreal performed the proedure on patients with both epithelial and multicystic peritoneal mesothelioma, administering the heated chemotherapeutic agent for a period of thirty minutes. They found that patients who had the procedure lived at least a year following the procedure, with 91 percent surviving for three years. The procedure was well tolerated, with no patients dying as a result. The research concluded that the protocol is a valid treatment.

An Italian study followed a slightly different protocol in which the chemotherapy drug used was cisplatin and it was administered for a period of 60 minutes. The treatment was followed in six mesothelioma patients and two lung cancer patients, and revealed a mean survival of 13.6 months, with no patient deaths or major complications resulting from the treatment.

The last of the three studies was conducted in Singapore, where several patients who had varying cancers of the peritoneal area were treated using a combination of cytoreductive surgery and heated chemotherapy. Though one patient suffered some complications, the others went through the procedure with no complications and all of the latter group lived for a minimum of one year following the treatment. This group of researchers also determined that the use of CRS/HIPEC offers good outcomes in which select patients can “achieve prolonged survival”.

Terri Oppenheimer

Terri Oppenheimer is an experienced blog writer, editor, and proofreader. She graduated from the College of William and Mary with a degree in English. She specializes in providing content for websites and finds tremendous enjoyment in the things she learns while doing her research. Her specific areas of expertise include health, medical research, and law.

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