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Study Shows that HIPEC Procedure Can Be Repeated With Good Outcomes

Dr. Paul Sugarbaker is renowned in the field of mesothelioma surgery for his groundbreaking surgical work in the treatment of this rare and deadly disease. Most recently he and his colleagues at the Program in Peritoneal Surface Oncology in Washington, D.C. have completed a study showing that patients suffering from peritoneal mesothelioma can have repeated surgical procedures in order to extend their rate of survival.

In their report published in a recent edition of the Annals of Surgical Oncology, Dr. Sugarbaker and his team show that patients who have been diagnosed with diffuse peritoneal mesothelioma can have repeated cytoreductive surgery and heated intraperitoneal chemotherapy more than once, and can not only do so safely but also can improve their odds of survival over a number of years.  The cytoreductive surgery is a debulking procedure that removes the maximum amount of tumorous material growing on the peritoneal lining. That procedure is then followed with a bath of heated chemotherapy drugs referred to as HIPEC before the surgical incision is closed. The combination of the two procedures is aimed at making sure that the maximum number of mesothelioma cells are killed during the single surgery, and has been shown to have good results and to significantly extend patients survival.

In comparing the survival rates and statistics regarding complications of patients who had the HIPEC procedure a second time after their mesothelioma returned rather than those who only had the procedure once, the group found that the second procedure resulted in no deaths within a month of the surgery and only a 2.3% rate of serious complications. The three-year survival rate for those having a second procedure was nearly identical to that of the group that had just one, showing that the second surgery can provide an average of an additional 54 months.

According to Chukwuemeka Ihemelandu, MD, “Iterative CRS and HIPEC can be performed safely and appear to have benefits with this group of patients showing an improved median survival.” The group did note that the surgery was more successful for those patients that had the epithelioid subtype of peritoneal mesothelioma and who were younger and who had had not serious postop complications. Women fared better than men, and the surgeries that had accomplished a complete or near-complete cytoreduction were the most successful.

Terri Oppenheimer

Terri Oppenheimer is an independent writer, editor and proofreader. She graduated from the College of William and Mary with a degree in English. Her dreams of a writing career were diverted by a need to pay her bills. She spent a few years providing copy for a major retailer, then landed a lucrative career in advertising sales. With college bills for all three of her kids paid, she left corporate America for a return to her original goal of writing. She specializes in providing content for websites and finds tremendous enjoyment in the things she learns while doing her research. Her specific areas of interest include health and fitness, medical research, and the law.

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