Welcome to Mesothelioma.net - Turning Hope and Faith into Action.


A pericardiectomy is a surgical procedure that removes part or all of the pericardium. The pericardium is the double layer of tissue surrounding the heart. This procedure treats several different conditions including one of the rarest types of mesothelioma, pericardial mesothelioma. For mesothelioma patients, this surgery may relieve symptoms and extend life expectancy.

Pericardial mesothelioma is a rare and aggressive cancer. A pericardiectomy is most often used to treat inflammation or fibrosis of the pericardium, regardless of the underlying cause. The procedure may also be used to treat the buildup of fluid in the pericardium. This condition is known as pericardial effusion. All of these conditions can have a serious impact on the heart. If left untreated, it could lead to heart failure and death. Pericardiectomy is a risky procedure with several possible complications. However, the risks of not performing it are often higher.

What Is a Pericardiectomy?

The pericardium is part of the mesothelium, the double-layered tissue that protects and surrounds most of the body’s organs. This double-layered tissue also lines the chest and abdominal cavities. When there is disease affecting this tissue, it may become inflamed, filled with fluid, or harden. All of these cause uncomfortable symptoms, but they also cause real damage to the heart. A pericardiectomy removes diseased tissue to relieve symptoms and prevent further damage. During a pericardiectomy, the surgeon may remove only diseased portions of the pericardium, or he or she may remove all of it.

What Pericardiectomy Treats

Pericariectomy surgery is used to treat serious conditions that are causing difficult symptoms. One of the most common conditions is constrictive pericarditis. Constrictive pericarditis is characterized by inflammation of the pericardium followed by stiffness and rigidity that constricts the heart. This condition is uncomfortable, but can also be fatal. Heart surgery and chest radiation are common causes of constrictive pericarditis, but it can also be caused by infections and mesothelioma, both pleural and pericardial mesothelioma.

The Procedure

There are different ways to perform a pericardiectomy. However, the typical way is through a median sternotomy. This means the surgeon makes an incision in the sternum to access the pericardium around the heart. The surgeon then makes cuts to remove the diseased tissue, wires the breastbone back together, and closes the incision with stitches.


A pericardiectomy is a major surgery that requires general anesthesia. Recovery can be difficult but is not as long as for other surgeries used to treat mesothelioma. Most patients will spend between five to seven days in the hospital. During the stay, patients will be monitored for complications and fluid will be drained from the chest cavity and around.

Once a patient is released from the hospital. he or she will be nearly fully recovered. Lifting may be restricted, but other normal activities are usually allowed. Limitations vary by patient. Patients in poor general health or with more advanced disease, such as late stage mesothelioma, may not fully recover for two months or more.

Risks and Complications

With any surgery there are risks. This is particularly true when the surgery is related to the heart. A pericardiectomy is a serious procedure only performed by experts in thoracic surgery. Possible complications include complications from anesthesia, bleeding, blood clots, abnormal heart rhythms, a buildup of fluid in the chest cavity and around the lungs, infection, and even death.

The risks associated with this procedure vary depending on the individual patients. Those with other health issues or with compromised immune systems may be at a greater risk for complications. If you are facing the choice of a pericardiectomy, talk with your doctor about your risks. You will need to weigh these risks against the benefits in order to make a fully informed decision. For most people with a diseased pericardium, the risks are worth the benefits of having it removed.

Benefits of a Pericardiectomy for Mesothelioma Patients

Mesothelioma patients often receive a pericardiectomy to relieve symptoms. Both pleural and pericardial mesothelioma may cause damage to the pericardium. This type of cancer can cause constrictive pericarditis, pericardial effusion, and tumors in the pericardium. These can cause serious symptoms like swelling, fatigue, chest pains, and difficulty breathing.

For mesothelioma patients experiencing pericardial effusion, a less invasive procedure is usually used first. A pericardiocentesis uses a needle to drain fluid buildup. However, if the fluid continues to accumulate, the patient may need a pericardiectomy to prevent recurrence and provide lasting relief.

Another benefit of a pericardiectomy for mesothelioma patients is extended life expectancy. If the patient has pericardial mesothelioma or pleural mesothelioma that has spread to the pericardium, removing the tissue can slow the spread of cancer to the rest of the body. This could extend the patient’s life expectancy. For some patients in the later stages of the disease, the procedure may only be palliative. However, for those in the earlier stages of cancer, the pericardiectomy may extend life by months or even years.

Pericardiectomy is one of many surgical procedures and treatments used for patients living with mesothelioma. The pericardium of the heart is affected in patients with both pleural and pericardial forms of mesothelioma. For most mesothelioma patients, the surgery’s risks are worth the potential benefits of the procedure. The ability to breathe and a reduction of pain levels add to the quality of life for a patient with this disease. For some, pericariectomy can even add to their life expectancy. If you are facing this procedure, be sure to ask questions and seek information so you can feel comfortable with moving ahead with treatment.

Page Edited by Dave Foster

Dave has been a mesothelioma Patient Advocate for over 10 years. He consistently attends all major national and international mesothelioma meetings. In doing so, he is able to stay on top of the latest treatments, clinical trials, and research results. He also personally meets with mesothelioma patients and their families and connects them with the best medical specialists and legal representatives available. Connect with Patient Advocate Dave Foster

Get Your FREE Resources Sent Overnight

  • New treatment options
  • Veterans benefits & claims
  • $30 Billion asbestos trust fund information

– Or Call –

Site Navigation

Where can I

Get Additional Help?

For over 20 years we’ve provided the best FREE resources to mesothelioma patients and loved ones. Our resources include information on the leading treatment options and best doctors in your area; lessons learned from survivors; claims and benefits specifically for Veterans; and how to access your share of billions of dollars in trust fund money.

Get Your FREE Resources Sent Overnight

  • New Treatment Options
  • Veteran's Benefits & Claims
  • $30 Billion Asbestos Trust Fund Information

– Or Call –

$30 Billion Asbestos Trusts
Get Started