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Page Updated: June 28, 2022

Mesothelioma Recurrence

Anne Courtney Page Medically Reviewed and Edited by Anne Courtney, AOCNP, DNP

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Fact Checked

This page has been fact-checked by a Doctor of nursing practice specializing in Oncology and has experience working with mesothelioma patients.

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Sources of information are listed at the bottom of the article. We make every attempt to keep our information accurate and up-to-date. 

Please Contact Us with any questions or comments.

A mesothelioma recurrence is when cancer returns after a period of remission. Recurrence is not a worry for most mesothelioma patients because remission is rare. Those who beat mesothelioma must be aware of the possibility of recurrence and work with their medical teams to prevent it.

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Understanding Recurrence

A cancer recurrence means the same cancer has returned after a period of time when it wasn’t detected. If you are diagnosed with early-stage mesothelioma that is treated aggressively until it can no longer be found in your body, that is called complete remission; however, you may not be completely cured because cancer could recur.[1]

A recurrence does not have to appear in the same part of the body where the cancer began. For example, if you recover from pleural mesothelioma, cancer could reoccur in the abdominal cavity. Your cancer would still be referred to as pleural but recurrent.

Cancer recurrence may be local, meaning it is present in the same part of the body. It is considered regional if it returns to lymph nodes close to where it originated. A distant recurrence is when the cancer returns to a completely different part of the body.[1]

Progression vs. Recurrence

Progression is another cancer care term that may be confused with recurrence. A return of cancer can only be called a recurrence after cancer cells were completely eliminated from the body. Progression describes cancer that has not been fully cured and gets worse.[1]

Complete remission from mesothelioma is so rare that this can be confusing. Treatment may result in partial remission, meaning that half or more of a tumor has been eliminated.

A partial remission may make you feel like you are healing; however, because the cancer has not been thoroughly eliminated, if it worsens, it has progressed, not recurred.

Treatment and Recurrence

Aggressive, multi-modal treatment is the best way to prevent a mesothelioma recurrence. Several treatments can eliminate cancer, including surgery, chemotherapy, and radiation.

One study of mesothelioma patients found good survival rates after extrapleural pneumonectomy (EPP), the most aggressive (and dangerous) surgery for mesothelioma.[2]

EPP removes nearly all the tissue from one side of the chest cavity, including the lung, pleura, and part of the diaphragm, which can be artificially reconstructed.

The surgeon may also remove lymph nodes during this procedure. Some patients in the study avoided recurrence for longer than patients unable to undergo the procedure with chemotherapy and radiation.

Stories of Survival

Although stories of survival are rare, some people have lived years after a mesothelioma diagnosis, some with recurrences and others totally cancer-free.

One patient developed peritoneal mesothelioma, which normally reduces life expectancy to months. This patient survived for nineteen years with no recurrences after initial treatment.[3]

This is practically unheard of with mesothelioma. There are also stories of patients going six and twelve years after diagnosis and treatment without a recurrence.

Controlling Mesothelioma

As treatments for this difficult cancer improve, more patients will face recurrence. As with many types of cancer, once a cure is found, recurrence becomes a common factor in long-term survival.

Mesothelioma specialists typically talk about controlling the disease rather than curing it. While a few people have been lucky, researchers don’t fully understand why.

However, advancements in mesothelioma treatment allow doctors to control the disease in their patients. They can help their patients live longer with the disease, which is a major improvement.

Coping with a Recurrence

As recurrences become more common in mesothelioma, patients must learn to cope with them. When your cancer is no longer detectable, it may feel like you are on top of the world.

If you find out it has returned, you may feel like you are falling all over again. It is important to stay on schedule with your surveillance scans and follow-up visits with your medical team to catch recurrence early.

Report any new or returning symptoms similar to your original diagnosis, and avoid smoking and try to maintain a healthy lifestyle.

If your cancer reoccurs, find a support network. Communicate with your medical team to make educated decisions about your treatment. It can be helpful to also care for your emotional health with things like therapy, meditation, or stress relief techniques.

Remember that recurrences may happen regardless of how well you took care of yourself.[4] You may not cure your cancer again, but if you take the right steps, you may live longer with it under control.

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Page Medically Reviewed and Edited by Anne Courtney, AOCNP, DNP

Anne Courtney

Anne Courtney has a Doctor of Nursing Practice degree and is an Advanced Oncology Certified Nurse Practitioner. She has years of oncology experience working with patients with malignant mesothelioma, as well as other types of cancer. Dr. Courtney currently works at University of Texas LIVESTRONG Cancer Institutes.

Connect with Doctor of Nursing Practice Anne Courtney
References
  1. American Cancer Society. (2016, February 12). What is Cancer Recurrence?
    Retrieved from: https://www.cancer.org/treatment/survivorship-during-and-after-treatment/understanding-recurrence/what-is-cancer-recurrence.html
  2. De Perrot, M., Feld, R., Cho, B.C.J., Bezjak, A., Anraku, M., Burkes, R., Roberts, H., Tsao, M.S., Leighl, N., Keshavjee, S., and Johnston, M.R. (2009). Trimodality Therapy With Induction Chemotherapy Followed by Extrapleural Pneumonectomy and Adjuvant High-Dose Hemithoracic Radiation for Malignant Pleural Mesothelioma. J. Clin. Oncol. 27(9), 1413-18.
    Retrieved from: https://ascopubs.org/doi/full/10.1200/jco.2008.17.5604
  3. Tandar, A., Abraham, G., Gurka, J., Wendel, M., and Stolbach, L. (2001, September). Recurrent Peritoneal Mesothelioma With Long-Delayed Recurrence. 33(3), 247-50.
    Retrieved from: https://www.ncbi.nlm.nih.gov/pubmed/11500619
  4. American Cancer Society. (2016, February 12). Coping with Cancer Recurrence.
    Retrieved from: https://www.cancer.org/treatment/survivorship-during-and-after-treatment/understanding-recurrence/coping-with-cancer-recurrence.html
View All References

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