Welcome to Mesothelioma.net - Turning Hope and Faith into Action.

Tubulopapillary Mesothelioma

Malignant mesothelioma can be differentiated in several ways, including by cell type. The most common cell type, epithelial or epithelioid mesothelioma, can be further divided into several different subtypes. The most common of these is tubulopapillary mesothelioma, which is characterized by tubules and papillary cell architecture.

There is some evidence that patients with the tubulopapillary subtype of pleural or peritoneal mesothelioma have a greater life expectancy, but this is not always the case. Investigating the cell type of mesothelioma is important for making an accurate diagnosis and for developing and planning the best treatments.

Epithelial Mesothelioma

There are three main types of mesothelioma as categorized by cell type: epithelial, sarcomatoid, and biphasic, which is a mixture of the other two. Epithelial cells are most commonly involved in mesothelioma, accounting for nearly three-quarters of diagnoses.

Tissue containing epithelial cells lines many parts of the body, from the skin and throat to most organs. The role they play is in protecting other tissues, by providing a barrier. They are healthy, normal cells that come in a variety of shapes and sizes, but they can become cancerous, as in the case of epithelial mesothelioma.

Epithelial mesothelioma is less aggressive than sarcomatoid. The cancerous epithelial cells grow and spread more slowly than those involved in sarcomatoid mesothelioma. It is still a very serious type of cancer, and one that will spread and metastasize, but patients with this cell type are likely to have a better prognosis.

Tubulopapillary Epithelial Cells

There are many subtypes of epithelial cells that can be involved in epithelial mesothelioma. These are characterized by different shapes and growth patterns. One of the most common epithelial subtypes is tubulopapillary. This type of mesothelioma exhibits cancer cells that grow papillary structures and smaller tubules. There may also be psammoma bodies—round gatherings or bodies of calcium—seen in biopsies of this type of mesothelioma. The cell structure and growth pattern of tubulopapillary mesothelioma can be mistaken for adenocarcinoma.

Diagnosing Tubulopapillary Mesothelioma

Diagnosing any kind of mesothelioma can be difficult for several reasons. Mesothelioma is rare, so it can often be mistaken for another type of cancer, like lung cancer. As with other types of mesothelioma, asbestos exposure is the most likely cause, so knowing that a patient has been exposed in the past can help make the diagnosis more accurate.

To diagnose mesothelioma in general, doctors need to perform a complete physical and then use imaging scans, like X-rays, MRIs, and CT scans to look for causes of symptoms, to rule out other conditions, and to detect any unusual growths that may be tumors.

If a growth is found, the next step in making a diagnosis is to remove a small sample, or perform a biopsy. A small piece of tissue can be examined under the microscope to determine the cells involved and, the type of cancer, and whether it is malignant or a benign growth. Diagnosing mesothelioma as tubulopapillary involves looking at the cells to identify the characteristic tubules and papillary structures and also to determine that the cells involved are epithelial rather than sarcomatoid.

Treating Tubulopapillary Mesothelioma

How tubulopapillary mesothelioma is treated depends a lot on the individual patient and the stage of the cancer. Most cases of mesothelioma are treated with a multimodal approach, using surgery if possible to remove as much of the cancerous tissue as possible and supplementing surgery with chemotherapy or radiation to kill any cells that couldn’t be removed.

The outlook for anyone with mesothelioma is generally poor. This is a difficult cancer to treat, and most people are diagnosed and begin treatment after it has already spread or even metastasized. Tubulopapillary mesothelioma has some of the longest life expectancies of all types of mesothelioma. This may be a result of the slower, less aggressive growth of the tumors, which makes treating it in a timely fashion easier.

If you were exposed to asbestos in the past, and if you have symptoms of mesothelioma, like coughing, chest pains, and shortness of breath, it is important to be screened as soon as possible. Diagnostic techniques are getting better all the time and new treatments are helping patients live longer and with a better quality of life. Getting an accurate diagnosis now is the best thing you can do.

Get Your FREE Resources Sent Overnight

resources-shot_optimized
  • New treatment options
  • Veterans benefits & claims
  • $30 Billion asbestos trust fund information

– Or Call –
1-800-692-8608


Site Navigation

Where can I

Get Additional Help?

For over 15 years, we’ve provided the best FREE resources to mesothelioma patients and loved ones. Our resources include information on the leading treatment options and best doctors in your area; lessons learned from survivors; claims and benefits specifically for Veterans; and how to access your share of billions of dollars in trust fund money.

Get Your FREE Resources Sent Overnight

resources-shot_optimized
  • New Treatment Options
  • Veteran's Benefits & Claims
  • $30 Billion Asbestos Trust Fund Information

– Or Call –
1-800-692-8608

We are here to help you

support_staff

If you've been diagnosed with asbestos-related cancer, contact us at 1-800-692-8608 to find out if you are eligible to receive compensation. You can also fill out the form above to receive FREE information.

Quick Compensation - $30 Billion Trusts
$30 Billion Asbestos Trusts
Get Started