Palliative Treatment for Mesothelioma
Page Medically Reviewed and Edited by Anne Courtney, AOCNP, DNP This page has been fact-checked by a Doctor of nursing practice specializing in Oncology and has experience working with mesothelioma patients.
Sources of information are listed at the bottom of the article. We make every attempt to keep our information accurate and up-to-date.
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The goals of palliative treatment for mesothelioma are to relieve side effects and symptoms and improve quality of life. Traditionally used in hospice care for end-stage patients, these supportive treatments are increasingly useful for patients in all stages.
- What is Palliative Treatment
- Why Palliative Care is Important
- Who Provides Palliative Treatments?
- Palliative Treatment in Hospice Care
- Palliative Treatments for Pleural Mesothelioma
- Palliative Treatments for Peritoneal Mesothelioma
- Palliative Treatments for Pericardial Mesothelioma
- Pain Management in Mesothelioma
- Complementary and Alternative Therapies
- Where Can I Get Additional Help?
What is Palliative Treatment?
Palliative treatment is any type of care provided for a patient with a serious or terminal illness to improve quality of life. Instead of solely treating a disease, it focuses on factors that affect symptoms as well as prioritizing personalized care. Treatment is geared towards what matters most to patients. This includes all kinds of supportive care:[1]
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- Physical and medical care
- Pain management
- Management of cancer side effects
- Management of treatment side effects
- Psychological, social, and spiritual care
While some strategies may overlap, palliative care is not the same as other cancer treatments. The goal of treatments that are not palliative is to cure, slow, or stop the progression of a disease. Many patients with mesothelioma benefit from both palliative and non-palliative treatments.
Why Palliative Care is Important
Studies find that malignant mesothelioma patients have a high burden of symptoms: shortness of breath, fatigue, chest pains, loss of appetite, and cough, among other less common symptoms. They also experience distress, uncertainty, and a sense of lack of control.
Management of symptoms to improve quality of life is the main reason to use palliative care. Patients may struggle with severe, uncomfortable, and painful side effects of cancer and its treatments without treatment for symptoms. Palliation can help patients physically but also give them better control over their quality of life, which improves mental health.
Historically, palliative care was reserved for patients in the latter stages of cancer. However, the literature supports the introduction of palliative care at the time of diagnosis, especially for those cancers that tend to be aggressive with shorter survival trends. Palliative care can work in conjunction with the medical and surgical oncology teams to provide patient-centered care. Mesothelioma is a particularly painful cancer, and palliation early on in the disease can be beneficial.
Studies have shown that cancer patients with early access to palliative care enjoyed a better quality of life and improved survival times.[2]
Who Provides Palliative Treatments?
Patients in need of palliative care will generally work with a specialist. Some centers have dedicated palliative care teams. They have specialty training in palliative care and can create a strategy with the patient and their family. If a dedicated team is unavailable, the medical care team can certainly have a more palliative approach and work to provide the support that best fits an individual’s goals.
Physicians provide the actual medical procedures. The palliative care specialist will also reach out to other caregivers to help implement the plan: pain specialists, holistic care providers, pharmacists, physical therapists, psychologists, spiritual leaders, and others.
Palliative Treatment in Hospice Care
Palliative treatments do not have to wait until a patient is in hospice care. Hospice may be in a medical facility or at home, but care is provided to patients at the end of their lives. Palliative care does not require enrollment into hospice.
However, Palliative care becomes especially important in hospice, where it provides relief, comfort, and the best possible quality of life for the time a patient has left.
Palliative Treatments for Pleural Mesothelioma
Patients living with pleural mesothelioma experience several difficult symptoms, including pain, a relentless cough, and difficulty breathing. Several treatments, including surgery, chemotherapy, and radiation therapy, can be used for relief and palliation:
- Thoracentesis. This is the draining of fluid from the chest cavity, a typical source of discomfort, pain, and difficulty breathing. The surgery is minimally invasive, using a thin needle.[3]
- Pleurodesis. To prevent recurring fluid buildup, a doctor may insert a tube to inject a medicine that causes the pleural tissue to adhere to the chest wall.[3]
- Pleurectomy/decortication. This surgery can be used to slow disease progression but also to palliate. Removing cancerous tissue helps to relieve symptoms.[4]
- Chemotherapy. Chemotherapy can be used alone to reduce tumor size, which may relieve some symptoms. The downside is that it causes side effects that patients find difficult to tolerate.
- Radiation therapy. When focused on the tumor in the chest, radiation can shrink tumors and relieve the pressure they put on surrounding tissues, relieving pain. Studies show radiation is particularly useful in relieving pain in localized areas.[5]
Palliative Treatments for Peritoneal Mesothelioma
Many of the same strategies used for pleural mesothelioma palliation can be applied to the peritoneal patient. Paracentesis is the term for removing fluid from the abdomen.[4] Standard chemotherapy may provide some benefits, but radiation is not generally used for peritoneal mesothelioma.
The buildup of fluid in the abdomen, known as ascites, can be particularly uncomfortable for peritoneal patients. Specialists who provide HIPEC, a debulking surgery followed by heated chemotherapy, may offer this service for palliation. It is generally used to slow or cure the cancer, but studies have also found it can improve quality of life as a palliative treatment.[6]
Palliative Treatments for Pericardial Mesothelioma
Managing this rare type of mesothelioma is especially challenging because it is so close to the heart. A percardiocentisis a surgical procedure that can be used to drain fluid from around the heart, which relieves pressure and pain.[3] Chemotherapy may also help relieve symptoms, but radiation is ineffective with pericardial mesothelioma.
A surgical procedure known as a pericardiectomy may help relieve symptoms specific to this type of mesothelioma. It involves removing part or all of the pericardium around the heart. This may help relieve pressure on the heart, which is both uncomfortable and dangerous.[7]
Pain Management in Mesothelioma
For any type of mesothelioma, pain is a major symptom and focus of palliative treatment. The medical treatments used for each type can help relieve pain but are often not adequate. Medications and other management strategies can help reduce pain or make it more tolerable:
- Over-the-counter pain medications, including acetaminophen and ibuprofen
- Prescription opioids for more moderate, severe, or breakthrough pain
- Nerve blocks, which are injected and block pain signals
- Cervical cordotomy, which involves creating a permanent lesion in the spine and has shown beneficial to mesothelioma patients[8]
Complementary and Alternative Therapies
While most complementary and alternative (CAM) practices are unproven to help treat cancer, they can help manage symptoms and play an important role in palliative care.
For example, a study from MD Anderson Cancer Center included 375 cancer patients and found that acupuncture relieved several symptoms: fatigue, hot flashes, numbness, nausea, and dry mouth.[9]
CAM may also include aromatherapy, massage therapy, herbal supplements, and other strategies. Patients may have a CAM specialist on their treatment or palliative care team. Some CAM practices may help some patients feel better or not work for others. Most are safe to try, though.
Palliative treatments are essential for helping mesothelioma patients enjoy a better quality of life. This is a devastating disease that is most often terminal but also very painful physically. Palliative care can provide psychological and spiritual assistance and medical treatments to relieve symptoms.
Page Medically Reviewed and Edited by Anne Courtney, AOCNP, DNP
Anne Courtney has a Doctor of Nursing Practice degree and is an Advanced Oncology Certified Nurse Practitioner. She has years of oncology experience working with patients with malignant mesothelioma, as well as other types of cancer. Dr. Courtney currently works at University of Texas LIVESTRONG Cancer Institutes.