Robert C. Miller, MD, MBA, FASTRO
Dr. Robert C. Miller is a nationally recognized radiation oncologist and the Medical Director of the Maryland Proton Treatment Center in Baltimore, Maryland. He is also a Professor in the University of Maryland School of Medicine Department of Radiation Oncology.[1]
Dr. Miller has extensive experience in cancer care and using radiation therapy for the treatment of malignant pleural mesothelioma, lung cancer, and other thoracic malignancies. His primary focus is on mitigation of radiation normal tissue injury.
The Maryland Proton Treatment Center is the first in the Baltimore-Washington region to offer proton therapy. It began treating patients in 2016 and offers pencil-beam scanning as well as intensity-modulated proton therapy. These are the most precise treatments available, delivering increased doses of radiation that stop at the tumor site, protecting surrounding, normal tissue.[1]
Education and Career
Rather than pursuing medicine, Dr. Miller began his scientific career as a medical physicist at the University of Kentucky. He then earned his medical degree there, as well as an MBA degree from Oxford University in the United Kingdom.[1]
He served at the Mayo Clinic for 25 years, conducting extensive clinical research on the use of compounds to mitigate the risk of normal tissue injury in patients undergoing radiation therapy. He also served as the national principal investigator/study chairman for 5 NIH-funded national Phase III cooperative group clinical trials before joining the University of Maryland.[2]
Professional Activities and Memberships
In addition to his practice, research, and leadership in the field of radiation oncology, Dr. Miller is the founding editor-in-chief of the American Society for Radiation Oncology’s third academic journal, Advanced in Radiation Oncology. While he was with the Mayo Clinic he was vice chair for regional practices, medical director at the Northfield campus, vice chair of the board of trustees at the Albert Lee campus, and Mayo Health System clinical liaison. He was also vice chair for research (particles), an associate fellow at the University of Oxford Particle Therapy Research Institute, and chair of the Data Safety Monitoring Board for the Proton Collaborative.[2]
Research
Dr. Miller is a prolific researcher who has led five National Cancer Institute-funded multi-institutional phase 3 cooperative group trials examining the effectiveness of drugs in the mitigation of radiation injury. His current focus is on health disparities in Appalachia, he has also been a leader in particle therapy and was an early advocate for using data science to improve health care. He is the author of more than 170 peer-reviewed papers.[]
His recent publications include:[3]
- Lindborg SR, Goyal NA, Katz J, Burford M, Li J, Kaspi H, Abramov N, Boulanger B, Berry JD, Nicholson K, Mozaffar T, Miller R, Jenkins L, Baloh RH, Lewis R, Staff NP, Owegi MA, Dagher B, Blondheim-Shraga NR, Gothelf Y, Levy YS, Kern R, Aricha R, Windebank AJ, Bowser R, Brown RH Jr, Cudkowicz ME. Debamestrocel multimodal effects on biomarker pathways in amyotrophic lateral sclerosis are linked to clinical outcomes. Muscle Nerve. 2024 Apr 9 Epub 2024 Apr 09
View PubMed - Liu S, Wen A, Wang L, He H, Fu S, Miller R, Williams A, Harris D, Kavuluru R, Liu M, Abu-El-Rub N, Schutte D, Zhang R, Rouhizadeh M, Osborne JD, He Y, Topaloglu U, Hong SS, Saltz JH, Schaffter T, Pfaff E, Chute CG, Duong T, Haendel MA, Fuentes R, Szolovits P, Xu H, Liu H. An open natural language processing (NLP) framework for EHR-based clinical research: a case demonstration using the National COVID Cohort Collaborative (N3C). J Am Med Inform Assoc. 2023 Nov 17; 30 (12):2036-2040
View PubMed - Smith RS, Foster NR, Jatoi A, Thome SD, Miller RC. Incidence of Brain Metastasis as First Event in Patients with Esophageal Carcinoma: a Report from Three Prospective Alliance Clinical Trials. J Gastrointest Cancer. 2023 Sep; 54 (3):846-854 Epub 2022 Oct 17
View PubMed - Savla B, Hamza MA, Yacubovich D, Cobbs S, Petrovska L, Scilla KA, Burrows W, Mehra R, Miller RC, Rolfo C, Bentzen SM, Mohindra P, Vyfhuis MAL. The Effect of Body Mass Index and Residence in Food Priority Areas on Patterns-of-Care and Cancer Outcomes in Patients With Stage III Non-Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys. 2023 May 1; 116 (1):50-59 Epub 2023 Jan 28
View PubMed - Chauhan K, Ebner DK, Tzou K, Ryan K, May J, Kaleem T, Miller D, Stross W, Malouff TD, Landy R, Strong G, Herchko S, Serago C, Trifiletti DM, Miller RC, Buskirk S, Waddle MR. Assessment of bladder filling during prostate cancer radiation therapy with ultrasound and cone-beam CT. Front Oncol. 2023; 13:1200270 Epub 2023 July 27
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