Timothy S. Blackwell, MD
Dr. Timothy S. Blackwell is a pulmonologist and critical care medicine specialist who is the chair of the University of Michigan’s Department of Internal Medicine. He is also the John G. Searle Professor of Internal Medicine at the University of Michigan’s Medical School. Dr. Blackwell is nationally recognized for his contributions to the clinical care of patients diagnosed with lung cancer and other pulmonary diseases, as well as for his mentoring of researchers and physician-scientists.[2]
Education and Career
Dr. Blackwell earned his undergraduate degree in Molecular Biology from Vanderbilt University and his medical degree from the University of Alabama at Birmingham. He completed an internship and residency in Internal Medicine at Washington University in St. Louis and completed a pulmonary and critical care fellowship at Vanderbilt.[1]
After completing his fellowship, Dr. Blackwell joined the staff at Vanderbilt University Hospital. Over the years his responsibilities expanded with his achievements until he rose to the position of physician-in-chief of the Vanderbilt Lung Institute and director of the Center for Lung Research. He was also named director of the Division of Allergy, Pulmonary, and Critical Care Medicine. He is credited with the expansion of the division, as well as with launching the Vanderbilt Lung Institute to seamlessly interconnect patient care delivery in Pulmonary Medicine, Allergy, and Immunology with Thoracic Surgery.[1]
Professional Memberships and Activities
Dr. Blackwell is an active member of several professional medical organizations and participates in numerous professional activities. Among these, he is a fellow of the American Association for the Advancement of Science and he chaired the Lung Injury, Repair, and Remodeling Study Section of the National Heart, Lung, and Blood Institute where he is a member of the Board of External Experts.[1]
Research
Dr. Blackwell is dedicated to investigating the pathobiology of lung diseases, including interstitial lung diseases, chronic obstructive pulmonary disease (COPD), acute lung injury, and lung cancer. He uses basic and translational science approaches and has authored nearly 300 peer-reviewed papers, as well as four book chapters.[1]
His publications include:[3]
Cell-type-specific and disease-associated expression quantitative trait loci in the human lung. Natri HM, Del Azodi CB, Peter L, Taylor CJ, Chugh S, Kendle R, Chung MI, Flaherty DK, Matlock BK, Calvi CL, Blackwell TS, Ware LB, Bacchetta M, Walia R, Shaver CM, Kropski JA, McCarthy DJ, Banovich NE.Nat Genet. 2024 Mar 28. doi: 10.1038/s41588-024-01702-0. Online ahead of print.PMID: 38548990
Repetitive Sulfur Dioxide Exposure in Mice Models Post-Deployment Respiratory Syndrome. Gutor SS, Salinas RI, Nichols DS, Bazzano JMR, Han W, Gokey JJ, Vasiukov G, West JD, Newcomb DC, Dikalova AE, Richmond BW, Dikalov SI, Blackwell TS, Polosukhin VV.Am J Physiol Lung Cell Mol Physiol. 2024 Feb 27. doi: 10.1152/ajplung.00239.2023. Online ahead of print.PMID: 38410870
Image-based spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis. Vannan A, Lyu R, Williams AL, Negretti NM, Mee ED, Hirsh J, Hirsh S, Nichols DS, Calvi CL, Taylor CJ, Polosukhin VV, Serezani AP, McCall AS, Gokey JJ, Shim H, Ware LB, Bacchetta MJ, Shaver CM, Blackwell TS, Walia R, Sucre JM, Kropski JA, McCarthy DJ, Banovich NE.bioRxiv [Preprint]. 2023 Dec 17:2023.12.15.571954. doi: 10.1101/2023.12.15.571954.PMID: 38168317 Free PMC article. Preprint.
Development of a Peripherally Restricted 5-HT2B Partial Agonist for Treatment of Pulmonary Arterial Hypertension. Valentine MS, Bender AM, Shay S, Paffenroth KC, Gladson S, Dickerson JW, Watson KJ, Kapolka NJ, Boutaud O, Rook JM, Blackwell TS, Roth BL, Harrison FE, Austin ED, West JD, Lindsley CW, Merryman WD.JACC Basic Transl Sci. 2023 Sep 13;8(10):1379-1388. doi 10.1016/j.jacbts.2023.06.014. eCollection 2023 Oct.PMID: 38094686 Free PMC article.
Loss of p73 Expression Contributes to Chronic Obstructive Pulmonary Disease. Richmond BW, Marshall CB, Blackburn JB, Tufenkjian TS, Lehmann BD, Han W, Newcomb D, Gutor SS, Hunt RP, Michell DL, Vickers KC, Polosukhin VV, Blackwell TS, Pietenpol JA.Am J Respir Crit Care Med. 2024 Jan 15;209(2):153-163. doi: 10.1164/rccm.202303-0503OC.PMID: 37931077
