Sean Dineen, MD
Dr. Sean Dineen is a surgical oncologist at the Moffitt Cancer Center in Tampa, Florida. He specializes in surgery for patients with gastrointestinal and peritoneal surface malignancies, including peritoneal mesothelioma. He is particularly skilled in the highly effective procedure known as CRS/HIPEC, or cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.[1]
Education and Career
Dr. Dineen earned his medical degree at the University of Louisville, then completed his residency in General Surgery at UT Southwestern in Dallas. His program extended into a research fellowship focused on the tumor microenvironment.
His interest in the topic extended into his fellowship in Complex General Surgical Oncology at MD Anderson Comprehensive Cancer Center, where he was recognized for Clinical Excellence by the Department of Surgery.[1]
After completing his education, Dr. Dineen went on to become the Medical Director of the Multidisciplinary Clinic at Markey Cancer Center at the University of Kentucky.
Dr. Dineen is now a surgical oncologist and Senior Member of the Gastrointestinal Oncology Department at the Moffitt Cancer Center in Tampa. He is also the Program Director of the Complex General Surgical Oncology Fellowship.
Dr. Dineen specializes in treating peritoneal surface malignancies. These include appendiceal cancer, peritoneal mesothelioma, gastric cancers with peritoneal metastases, and pseudomyxoma peritonei.
What is CRS/HIPEC?
CRS/HIPEC, or cytoreductive surgery and hyperthermic intraperitoneal chemotherapy, is one of Dr. Dineen’s areas of special expertise. It is a procedure that combines surgery to remove all visible malignant cells from the abdominal region, followed by a heated bath of chemotherapy.
CRS/HIPEC has proven extremely effective in the treatment of malignant peritoneal mesothelioma, as the highly concentrated chemotherapy solution is delivered directly to the site where any remaining cancer cells may be, impacting them directly rather than systemically. This means fewer side effects, better outcomes, and improved quality of life for patients.[2]
Surgeons who perform CRS/HIPEC must be highly experienced in the procedure, and there are only a few cancer centers throughout the country where it is available. Dr. Dineen is part of Moffitt Cancer Center’s multidisciplinary team that assesses peritoneal mesothelioma patients’ needs to determine whether they are eligible for this protocol.
Research
Dr. Dineen’s research interests lie in the tumor and its local environment, and the exploration of how the two interact to promote cancer cells metastasizing to other parts of the body.
He has published numerous articles on the topic and presented both nationally and internationally on the topic of both gastrointestinal and peritoneal cancers and other diseases.
Professional Memberships
Dr. Dineen is a member of the American College of Surgeons (ACS), the American Hepato-Pancreato-Biliary Association (AHPBA), and the Society for Surgeons of the Alimentary Tract (SSAT).[1]
