Jack Elias, MD
Dr. Jack Elias is an immunobiologist and a renowned scientist with a focus on pulmonary and critical care medicine. He is the Senior Health Advisor at Brown University. Throughout his long career, he specialized in treating a wide variety of lung ailments and conducted research on conditions including lung cancer, lung injuries, and chronic obstructive pulmonary disease. He is also working to expand translational research and to train the next generation of physician-scientists.[1]
Education and Career
Dr. Elias earned both his undergraduate and medical degrees at the University of Pennsylvania in Philadelphia. He completed an internship and junior residency at Tufts-New England Medical Center and a senior residency and fellowships in Allergy and Immunology and Pulmonary and Critical Care Medicine at the Hospital of the University of Pennsylvania.[1]
Following completion of his medical education and training, Dr. Elias became an Assistant Professor and then an Associate Professor in the Section of Pulmonary and Critical Care Medicine at the University of Pennsylvania School of Medicine.
He later accepted a role at Yale University School of Medicine and Yale New Haven Hospital, where he was named the Waldemar Von Zedtwitz Professor at Yale University, Chairman of Medicine at Yale University School of Medicine, and the Physician-in-Chief at Yale New Haven Hospital before joining Brown University.[1]
Dr. Elias has held many notable professional titles and responsibilities, including acting as a Councilor of the Association of American Physicians as well as its president.
He has served on the Lung Biology and Pathology Study Section of the National Institutes of Health, numerous advisory boards, and was an ad-hoc participant in the Council of the National Institute of Allergy and Infectious Diseases. He was also selected to the Council of the National Heart, Lung, and Blood Institute.[1]
Dr. Elias currently holds several positions at Brown University:
- Senior Vice President for Health Affairs
- Dean of Medicine and Biological Sciences
- Frank L. Day Professor of Biology
- Professor of Medicine
He is also the Waldemar Von Zedtzwitz Professor Emeritus of Medicine at Yale University School of Medicine.
Professional Memberships
Dr. Elias has been a member of many professional organizations throughout his career, including:[2]
- Association of American Physicians
- National Institute of Health/National Heart, Lung, Blood Institute (Advisor)
- Journal of Allergy and Clinical Immunology (Board Member)
- CT Academy of Science and Engineering
- National Institutes of Health (Liaison)
- American Society of Allergy, Asthma, and Immunology
- American Society for Clinical Investigation
- American Thoracic Society
- American College of Physicians
- American College of Chest Physicians
- American Federation for Clinical Research
- Federation of Societies for Experimental Biology
- American Association of Immunologists
Research
Dr. Elias researches conditions including lung cancer and lung injuries, chronic obstructive pulmonary disease, pneumonia, pulmonary fibrosis, and asthma.
His NIH-funded laboratory focuses on the cell and molecular biology of lung injury and repair, including a recent focus on the biology of chitinases and chitinase-like proteins and their role in pulmonary diseases. He and his colleagues have made great strides in the development of new drugs to treat these illnesses and injuries.[2]
As part of his translational research focus, Dr. Elias has been involved in founding biomedical companies, like Ocean Biomedical.
His most recent publications include:[3]
Mesenchymal Stem Cells Attenuate Asthmatic Inflammation and Airway Remodeling by Modulating Macrophages/Monocytes in the IL-13-Overexpressing Mouse Model. Yosep Mo, Yujin Kim, Ji-Young Bang, Jiung Jung, Chun-Geun Lee, Jack A Elias, Hye-Ryun Kang>; Immune Network. 2022 Oct 1
Host chitinase 3-like-1 is a universal therapeutic target for SARS-CoV-2 viral variants in COVID-19. Suchitra Kamle, Bing Ma, Chang Min Lee, Gail Schor, Yang Zhou, Chun Geun Lee, Jack A Elias>;Elife. 2022 Jun 23
Mesenchymal stem cells exert their anti-asthmatic effects through macrophage modulation in a murine chronic asthma model. Ruth Lee Kim, Ji-Young Bang, Jeonghyeon Kim, Yosep Mo, Yujin Kim, Chun-Geun Lee, Jack A Elias, Hye Young Kim, Hye-Ryun Kang>; Scientific Reports. 2022 Jun 13
