James D. Luketich, MD
Dr. James D. Luketich is a thoracic and cardiothoracic surgeon in the Department of Cardiothoracic Surgery at the University of Pittsburgh School of Medicine where he holds the title of Henry T. Bahnson Professor of Cardiothoracic Surgery. Dr. Luketich specializes in treating all types of thoracic malignancies, including lung cancer and malignant pleural mesothelioma, as well as esophageal cancer.[1]
Dr. Luketich has particular expertise in the multi-disciplinary management of lung and other cancers, combining chemotherapy and radiation with minimally invasive surgical techniques to provide his patients with the best possible outcomes.
Education and Career
Dr. Luketich completed an undergraduate degree at Old Dominion University in Norfolk, Virginia; a master’s degree in biochemistry from Vanderbilt University; and received a medical degree at the Medical College of Pennsylvania in Philadelphia, from which he graduated Magna Cum Laude. He completed an internship and residency at the Hospital of the University of Pennsylvania in Philadelphia and fellowships in Thoracic and Cardiothoracic Surgery at Cleveland Clinic in Ohio, Cornell University Medical Center in New York, and Memorial Sloan-Kettering Cancer Center in New York.[1]
Dr. Luketich is on the editorial board of several prestigious medical journals, including the Annals of Surgery and The Journal for Thoracic and Cardiovascular Surgery.[1]
Professional Memberships
Dr. Luketich is a Fellow of the American College of Surgeons. He enjoys membership in several prestigious surgical and medical societies, including:[1]
- American Surgical Association
- American Association for Thoracic Surgery
- Society of Thoracic Surgeons
- American Association for Cancer Research
- American College of Chest Physicians
- American College of Gastroenterology
- American Federation for Clinical Research
- American Society of Bariatric Surgery
- American Society of Clinical Oncology
- American Thoracic Society
- Esophageal Surgery Club
- General Thoracic Surgical Club
- International Society for the Study of Lung Cancer
- International Society for Diseases of the Esophagus,
- Medical College of Pennsylvania Alumni Association
- New York Society for Thoracic Surgery
- Pennsylvania Association for Thoracic Surgery
- Pennsylvania Medical Society
- Pennsylvania Oncologic Society
- Society of American Gastrointestinal Endoscopic Surgeons,
- Society of Laparo-endoscopic Surgeons
- Society of Surgical Oncology
- Society of Thoracic Surgeons
- Society for Surgery of the Alimentary Tract
- TRIAD International Association for Minimal Access Thoracic Surgery
Research
Dr. Luketich is actively engaged in clinical research and is currently an investigator or principal investigator on several NIH grants. His interests include benign and malignant diseases of the lungs and esophagus, and how to improve patient outcomes through the use of robotic-assisted surgical technology.[1]
His publications include:[2]
Completion of accrual for Thoracic Surgical Oncology Group 102: One small step forward for thoracic clinical trials. Huang J, Jones DR; Thoracic Surgical Oncology Group 102 Investigators; Thoracic Surgical Oncology Group Executive Board. J Thorac Cardiovasc Surg. 2024 Jan 29:S0022-5223(24)00092-8. doi: 10.1016/j.jtcvs.2024.01.034. Online ahead of print.PMID: 38295952 No abstract available.
Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells. Shan F, Cillo AR, Cardello C, Yuan DY, Kunning SR, Cui J, Lampenfeld C, Williams AM, McDonough AP, Pennathur A, Luketich JD, Kirkwood JM, Ferris RL, Bruno TC, Workman CJ, Benos PV, Vignali DAA.Sci Immunol. 2023 Sep 15;8(87): eadf6717. doi: 10.1126/sciimmunol.adf6717. Epub 2023 Sep 15.PMID: 37713508
A maladaptive pleural environment suppresses preexisting anti-tumor activity of pleural infiltrating T cells. Donnenberg VS, Luketich JD, Sultan I, Lister J, Bartlett DL, Ghosh S, Donnenberg AD.Front Immunol. 2023 Mar 30;14:1157697. doi: 10.3389/fimmu.2023.1157697. eCollection 2023.PMID: 37063842 Free PMC article.
Carcinogen 4-Nitroquinoline Oxide (4-NQO) Induces Oncostatin-M (OSM) in Esophageal Cells. Mukherjee A, Epperly MW, Fisher R, Shields D, Hou W, Pennathur A, Luketich J, Wang H, Greenberger JS. In Vivo. 2023 Mar-Apr;37(2):506-518. doi: 10.21873/invivo.13108.PMID: 36881075 Free PMC article.
Evaluation of electromagnetic navigational bronchoscopic biopsy of lung lesions performed by a thoracic surgical service. Witek TD, Pennathur A, Brynien D, Luketich JD, Scaife M, Azar D, Schuchert MJ, Gooding WE, Awais O.Surgery. 2023 May;173(5):1275-1280. doi: 10.1016/j.surg.2022.11.036. Epub 2023 Feb 14.PMID: 36797158
Comparison of robotic-assisted minimally invasive esophagectomy versus minimally invasive esophagectomy: A propensity-matched study from a single high-volume institution. Ekeke CN, Kuiper GM, Luketich JD, Ruppert KM, Copelli SJ, Baker N, Levy RM, Awais O, Christie NA, Dhupar R, Pennathur A, Sarkaria IS. J Thorac Cardiovasc Surg. 2023 Aug;166(2):374-382.e1. doi 10.1016/j.jtcvs.2022.11.027. Epub 2022 Dec 5.PMID: 36732144
Effects of Intraoperative Support Strategies on Endothelial Injury and Clinical Lung Transplant Outcomes. Coster JN, Noda K, Ryan JP, Chan EG, Furukawa M, Luketich JD, Sanchez PG.Semin Thorac Cardiovasc Surg. 2023 Jan 28:S1043-0679(23)00001-1. doi 10.1053/j.semtcvs.2022.09.016. Online ahead of print.PMID: 36716942
